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爱斯万与其他药物有什么相互作用?-福冠堂大药房
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爱斯万与其他药物有什么相互作用?

福冠堂大药房 2013-01-22


爱斯万与哪些药物有相互作用?

  你好!爱斯万的药物相互作用如下:

  (1)不得与下列药物合用

  药品名称 临床症状,处理措施 机理,危险因素

  氟尿嘧啶类抗肿瘤药

  氟尿嘧啶(5-Fu等)

  替加氟尿嘧啶复方制剂(UFT等)

  替加氟(Futraful)

  去氧氟尿苷(Furtulon)

  卡培他滨(Xeloda)

  卡莫氟(Mifurol) 合并用药早期即可导致严重的血液系统障碍以及腹泻、口腔炎等消化道功能障碍。

  停用本品后至少间隔7天以上再使用其他药物。其他药物停用后,亦需间隔适当的时间再给予本品。 本品中的吉美嘧啶可抑制合用药物中5-FU的分解代谢,使血中5-FU浓度显著升高(参照药代动力学项)。

  亚叶酸+替加氟+尿嘧啶联合化疗

  (亚叶酸+UFT等)

  左亚叶酸钙+氟尿嘧啶联合化疗

  (左亚叶酸钙+5-FU)

  氟嘧啶类抗真菌药

  氟胞嘧啶

  (2)与下列药物合用时应慎重

  药品名称 临床症状,处理措施 机理,危险因素

  苯妥英钠 可发生苯妥英钠中毒(恶心、呕吐、眼球震颤、运动障碍等)。严密观察患者状态,发现异常立即停用本品并采取适当的措施。 替加氟可抑制苯妥英钠代谢,使其血药浓度升高

  双香豆素钾 本品可增强双香豆素的作用,导致凝血功能异常。 机理不明

  其他抗肿瘤药

  放射线照射等 可增强血液系统、消化系统的副作用。注意观察患者的状态,发现异常应采取减量或停药等适当的措施。 副作用相互增强。
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